POTENCY ASSIGNMENT OF ANTHELMINTHIC DRUGS IN TELAZIOSISOF CATTLE

Abstract

The article presents data of the potency assignment of anthelminthic drugs in telaziosis of cattle. The comparative effectiveness of various forms of macrocyclic lactones against bovine telaziosis has been studied. The absolute extensive efficiency of anthelminthic drugs against telaziosis pathogens has been ascertain. The species composition of helminths has been determined on the territory of Chelyabinsk region. The causative agents of telaziosis are two types of helminths - Thelaziagulosa and Th. Skrjabini, while the infestation of cattle in individual farms can reach 30%. In the absence of treatment for this disease, the animal may lose its eyesight, reduce weight gain and milk yield and, as a result, be prematurely culled from the herd. Preparations based on macrocyclic lactones, such as ivermectin, are actively used for the treatment of telyaziosis in animals. As a result, accelerated regeneration of damaged eye tissues was observed. But these drugs are injected subcutaneously or intramuscularly to animals, and the disadvantage of such methods is a sufficiently strong pain and inflammatory reaction in animals, which creates an additional stress factor. In this regard, new anthelminthic preparations in the form of aqueous emulsions with nematocidal properties were used at the same time. The obtained data are allowed to conclude that all the tested compounds have pronounced anti-bacterial properties. The extensivity of injectable forms ranged from 97.0 to 88.4 %,